HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway
Abstract Homeobox A5 (HOXA5) is a Kids Water Bottle transcription factor in mammalian and can regulate cell differentiation, proliferation, and apoptosis as well as tumorigenesis.However, little is known on whether and how HOXA5 can regulate the malignant behaviors of cholangiocarcinoma.The methylation levels of HOXA5 were evaluated by methylation